Ttc9a

WebFeb 27, 2015 · Tetratricopeptide repeat domain 9A (TTC9A) is a target gene of estrogen and progesterone.It is over-expressed in breast cancer. However, little is known about the physiological function of TTC9A.The objectives of this study were to establish a Ttc9a knockout mouse model and to study the consequence of Ttc9a gene inactivation. The … WebAug 12, 2008 · TTC9A (1–100), which contains the first TPR domain, interacted with Tm5NM-1 to some extent but the interaction was weaker than TTC9A (1–115). Since the first TPR domain lies in residues 57–90, it is plausible that the first TPR domain is required for the interaction.

Tetratricopeptide repeat domain 9A negatively regulates estrogen ...

WebUniProtKB unreviewed (TrEMBL) Organism. Catharus fuscescens (Veery) Amino acids. 181. Protein existence. Predicted. Annotation score. 1/5. cindy\u0027s hallmark bend or https://unitybath.com

TTC9A deficiency induces estradiol-mediated changes in ... - PubMed

WebDC Field Value Language; dc.contributor.author: Lim, Lee Wei: en: dc.contributor.author: Shrestha, Smeeta: en: dc.contributor.author: Or, Yu Zuan: en: dc.contributor ... WebNumber of male and female pups from Ttc9A KO mice crosses. There is no 13 significant difference in the male and female offspring ratios from Ttc9a+/+ X Ttc9a+/+, 14 Ttc9a+/-X Ttc9a+/-and Ttc9a-/-X Ttc9a-/- crosses. 15 16 (Table S3) Supplementary Table 3. Organ Weights of female Ttc9a KO mice at 3 weeks 17 and 6 weeks of age 18 WebTTC9A deficient mammary gland showed significant increase in mammary ductal elongation and branching on estrogen and progesterone treatment, demonstrating aberration in hormone receptor signaling in absence of TTC9A.These observations suggest that TTC9A negatively regulates mammary gland development and the possibility that … cindy\u0027s hair salon game

TTC9A deficiency induces estradiol-mediated changes in

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Ttc9a

HKU Scholars Hub: TTC9A deficiency induces estradiol-mediated …

WebTTC9A through estradiol action in emotional control. Although we know that Ttc9a-/- induces anxiety-like behavior through the effect of estradiol on serotonergic system 9, the … WebApr 1, 2024 · Since Ttc9a is induced by estrogen in estrogen target tissues, these results suggest that Ttc9a is a negative regulator of estrogen function through a negative …

Ttc9a

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WebThe involvement of tetratricopeptide repeat domain 9A (TTC9A) deficiency in anxiety-like responses and behavioral despair through estradiol action on the serotonergic system has been reported. Emerging evidence suggests that estradiol is a potent modulator of neuroplasticity. As estradiol and neurop … WebPrimePCR™ Template for Probe Assay: TTC9, Human Reaction: 200 x 20 µl reactions Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.

WebTTC9A deficient mammary gland showed significant increase in mammary ductal elongation and branching on estrogen and progesterone treatment, demonstrating … WebApr 1, 2024 · In brief, Ttc9a-/-and wildtype female mice were subjected to ovariectomy (OVX) as reported (Lim et al., 2016; Lin et al., 2001). After a 10-day recovery period, mice were …

WebTTC9A to be 222 aa. Using mouse polyclonal antibody generated against TTC9A protein, TTC9A was shown to be ubiquitously expressed in human tissues. In breast cancer cells, TTC9A was predominantly concentrated to the endoplasmic reticulum and was regulated by a number of factors, such as growth factors, serum factors and steroid hormones [2]. WebSep 6, 2024 · It is plausible therefore that TTC9A negatively regulates ERalpha activity through interacting with co-chaperone proteins such as FKBP38 and FKBP51. TTC9A acts …

WebThe involvement of tetratricopeptide repeat domain 9A (TTC9A) deficiency in anxiety-like responses and behavioral despair through estradiol action on the serotonergic system …

WebSep 14, 2012 · 1. Introduction. Tetratricopeptide repeat domain 9A (TTC9A) is a member of TTC9 family proteins that also include TTC9B and TTC9C. Human TTC9A gene was first identified by sequence analysis of a cDNA clone from a brain cDNA library .It was confirmed to code for a 222 amino acid TTC9A protein in human using mouse polyclonal antibody … cindy\u0027s hallmark 185th hillsboro orWebAnti-TTC9 antibody produced in rabbit Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution; Synonyms: Anti … diabetic hot cross bunsWebDC Field Value Language; dc.contributor.author: Shrestha, Smeeta: en: dc.contributor.author: Sun, Yang: en: dc.contributor.author: Lufkin, Thomas: en: dc.contributor ... cindy\\u0027s hair pros chester vaWebApr 1, 2024 · In brief, Ttc9a-/-and wildtype female mice were subjected to ovariectomy (OVX) as reported (Lim et al., 2016; Lin et al., 2001). After a 10-day recovery period, mice were administered a subcutaneous injection of either 10 μg/kg 17-β-estradiol benzoate . Effects of Ttc9a-/-and estradiol modulation on tail suspension immobility cindy\u0027s hair salon fernandina beach flWebTo understand the effects of TTC9A and estradiol modulation on neuroplasticity functions, we performed a behavioral analysis of tail suspension immobility and neuroplasticity-related gene expression study of brain samples collected in a previous study involving ovariectomized (OVX) Ttc9a-/- mice with estradiol or vehicle treatment. diabetic hot flash without sweatingWebEmerging evidence suggests that estradiol is a potent modulator of neuroplasticity. As estradiol and neuroplasticity changes are both implicated in mood regulation, and estradiol activity is negatively regulated by TTC9A, we hypothesized that the behavioral changes induced by Ttc9a-/- is also mediated by neuroplasticity-related mechanisms. cindy\\u0027s hallmark hillsboroWebApr 1, 2024 · We aimed to investigate the interactive roles of TTC9A and estradiol modulation on behavioral neuroplasticity. The tail suspension immobility data and brain … diabetic hot flashes sweats